Biological sequence analysis

Durbin, Richard

Biological sequence analysis probabalistic models of proteins and nucleic acids - Cambridge, Angleterre Cambridge University Press 1998 - xi, 356 p. Illustration 24 cm.

Probabilistic methods are assuming greater significance in the analysis of nucleotide sequence data. This book provides the first unified, up-to-date and self-contained account of such methods, and more generally of probabilistic methods of sequence analysis, presented in a Bayesian framework.

1. Introduction; 2. Pairwise sequence alignment; 3. Multiple alignments; 4. Hidden Markov models; 5. Hidden Markov models applied to biological sequences; 6. The Chomsky hierarchy of formal grammars; 7. RNA and stochastic context-free grammars; 8. Phylogenetic trees; 9. Phylogeny and alignment; Index.

9780521540797 0521540798


Amino acid sequence--Data processing
Nucleotide sequence--Data processing
Markov processes
Amino acid sequence--Statistical methods
Probabilities


Numerical analysis
Nucleotide sequence--Statistical methods


572.8633 / BIO