TY - BOOK AU - Durbin, Richard AU - Eddy, Sean R. AU - Krogh, Anders AU - Mitchison, Graeme TI - Biological sequence analysis: probabalistic models of proteins and nucleic acids SN - 9780521540797 U1 - 572.8633 PY - 1998/// CY - Cambridge, Angleterre PB - Cambridge University Press KW - Amino acid sequence--Data processing KW - Nucleotide sequence--Data processing KW - Markov processes KW - Amino acid sequence--Statistical methods KW - Probabilities KW - Numerical analysis KW - Nucleotide sequence--Statistical methods KW - N1 - Probabilistic methods are assuming greater significance in the analysis of nucleotide sequence data. This book provides the first unified, up-to-date and self-contained account of such methods, and more generally of probabilistic methods of sequence analysis, presented in a Bayesian framework N2 - 1. Introduction; 2. Pairwise sequence alignment; 3. Multiple alignments; 4. Hidden Markov models; 5. Hidden Markov models applied to biological sequences; 6. The Chomsky hierarchy of formal grammars; 7. RNA and stochastic context-free grammars; 8. Phylogenetic trees; 9. Phylogeny and alignment; Index ER -