000 02388cam a2200289 a 4500
999 _c48226
_d49773
003 ISURa
008 111012s2012
020 _a9781439809754
041 _aEnglish
082 0 0 _a572.8636
_bDRA
100 1 _aDrăghici, Sorin
_925130
245 1 0 _aStatistics and data analysis for microarrays using R and bioconductor
250 _a2nd ed.
260 _aBoca Raton
_bCRC Press
_c2012
300 _axlviii, 1042 p.
_c25 cm.
_e1CD-ROM
440 _aMathematical and Computational Biology Series
_925151
500 _a "Richly illustrated in color, Statistics and Data Analysis for Microarrays Using R and Bioconductor, Second Edition provides a clear and rigorous description of powerful analysis techniques and algorithms for mining and interpreting biological information. Omitting tedious details, heavy formalisms, and cryptic notations, the text takes a hands-on, example-based approach that teaches students the basics of R and
520 _a The Cell and Its Basic Mechanisms -- Microarrays -- Reliability and Reproducibility Issues in DNA Microarray Measurements -- Image Processing -- Introduction to R -- Bioconductor: Principles and Illustrations -- Elements of Statistics -- Probability Distributions -- Basic Statistics in R -- Statistical Hypothesis Testing -- Classical Approaches to Data Analysis -- Analysis of Variance (ANOVA) -- Linear Models in R -- Experiment Design -- Multiple Comparisons -- Analysis and Visualization Tools -- Cluster Analysis -- Quality Control -- Data Pre-Processing and Normalization. Methods for Selecting Differentially Regulated Genes -- The Gene Ontology (GO) -- Functional Analysis and Biological Interpretation of Microarray Data -- Uses, Misuses, and Abuses in GO Profiling -- A Comparison of Several Tools for Ontological Analysis -- Focused Microarrays -- Comparison and Selection -- ID Mapping Issues -- Pathway Analysis -- Machine Learning Techniques
630 0 0 _aBioconductor (Computer file)
_925131
650 0 _aDNA microarrays
_xStatistical methods..
_925132
650 0 _aMathematical statistics
_xData processing.
_925133
650 0 _aR (Computer program language)
_925134
650 7 _aSCIENCE / Biotechnology.
_2bisacsh
_925135
650 7 _aMATHEMATICS / Probability & Statistics / General.
_925136
650 7 _aSCIENCE / Life Sciences / Biology / General.
_925137
942 _2ddc
_cLN